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  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Fucoxanthin, Gemcitabine
Phytochemical Name Fucoxanthin (PubChem CID: 5281239 )
Anticancer drug Name Gemcitabine (PubChem CID: 60750 )
Structure of
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Structure of
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02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
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Enhancing Drug Efficacy
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Combination Pair ID: 914
Ref_1
Pair Name Fucoxanthin, Gemcitabine
Disease Info [ICD-11: 2C10] Pancreatic cancer Investigative
Biological Phenomena Induction-->Apoptosis
In Vitro Model MIA PaCa-2 Pancreatic ductal adenocarcinoma Homo sapiens (Human) CVCL_0428
PANC-1 Pancreatic ductal adenocarcinoma Homo sapiens (Human) CVCL_0480
Result Fucoxanthin improved the cytotoxicity of gemcitabine on human pancreatic cancer cells at concentrations that were not cytotoxic to non-cancer cells. Thus, fucoxanthin has the potential to be used as an adjunct in pancreatic cancer treatment.
03. Reference
No. Title Href
1 Gemcitabine‑fucoxanthin combination in human pancreatic cancer cells. Biomed Rep. 2023 Jun 1;19(1):46. doi: 10.3892/br.2023.1629. Click
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