TOP
Nav Bar
  1. General Info
  2. Effects Info
  3. Reference
Drug Interaction Details
01. General Information
Pair Name Fucoxanthin, Gemcitabine
Phytochemical Name Fucoxanthin (PubChem CID: 5281239 )
Anticancer drug Name Gemcitabine (PubChem CID: 60750 )
Structure of
Phytochemical		 2D-img
Download
2D MOL 3D MOL
Structure of
Anticancer Drug		 2D-img
Download
2D MOL 3D MOL
02. Combinatorial Therapeutic Effect(s)
Synergistic Effect
Hide/Show
Enhancing Drug Efficacy
Hide/Show
Combination Pair ID: 914
Ref_1
Pair Name Fucoxanthin, Gemcitabine
Disease Info [ICD-11: 2C10.Z] Pancreatic cancer Investigative
Biological Phenomena Induction-->Apoptosis
In Vitro Model MIA PaCa-2 Pancreatic ductal adenocarcinoma Homo sapiens (Human) CVCL_0428
PANC-1 Pancreatic ductal adenocarcinoma Homo sapiens (Human) CVCL_0480
Result Fucoxanthin improved the cytotoxicity of gemcitabine on human pancreatic cancer cells at concentrations that were not cytotoxic to non-cancer cells. Thus, fucoxanthin has the potential to be used as an adjunct in pancreatic cancer treatment.
03. Reference
No. Title Href
1 Gemcitabine‑fucoxanthin combination in human pancreatic cancer cells. Biomed Rep. 2023 Jun 1;19(1):46. doi: 10.3892/br.2023.1629. Click
It has been None visits since 2024.08
If you find any error in data or bug in web service, please kindly report it to Dr. Zhang
TOP